|    Bookmark This Site    
Header Main

High-dose Chemo Battles Recurrent Testicular Cancer

Penis AnatomyHigh-dose chemotherapy combined with a stem-cell transplant can boost survival in men who have had a relapse after being treated for testicular cancer, researchers report.

Most men with testicular cancer can be cured with the combination of surgery and chemotherapy. However, as many as 30% may require additional treatment, according to Dr. Lawrence H. Einhorn and associates from Indiana University Medical Center in Indianapolis.

In a 3-year study of 65 men suffering a cancer relapse, the men received high-dose chemotherapy followed by either a bone-marrow transplant or stem-cell transplant to replenish the immune system damaged by the chemotherapy, which can be extremely toxic.

More than 40% of patients had a complete response to the high-dose chemotherapy, the authors report, and another 20% had no evidence of tumor after additional surgery. Fifteen additional patients had a partial response.

Overall, nearly 60% of patients were continuously free of cancer after high-dose chemotherapy either alone or combined with other treatments, according to the report in the October issue of the Journal of Clinical Oncology.

Some of the side effects of the chemotherapy were fever, diarrhea, nausea, mouth sores or kidney toxicity, though none of the patients died from the treatment.

"This is a message of hope," Einhorn said in a statement issued by the journal. "For patients who are not cured with the initial chemotherapy, we can now tell them with confidence that there is more than a 50% chance they can still be cured with second-line therapy."

SOURCE: Journal of Clinical Oncology 2000;18:3346-3351.


Male Related Cancer Articles: Testicular Cancer
Testicular Cancer Articles
Icon News Doctors Say Fewer Men Dying of Testicular Cancer
Icon News Fertility Problems Linked to Testicular Cancer Risk
Icon News High-dose Chemo Battles Recurrent Testicular Cancer
Icon News Genetic Link for Testicular Cancer Found
Icon News Son's Testicular Cancer Worse Than Dad's
Icon News First Gene For Testicular Cancer Discovered
Icon News Why Bank Sperm? Sperm Banking Informaiton for Testicular Cancer Patients NEW!!
Icon News What are the testicles & What is Testicular Cancer?
Icon News

What are the risk factors for testicular cancer How is testicular cancer detected? What are symptoms of testicular cancer?
Icon News How is testicular cancer diagnosed?
Icon News

How is testicular cancer treated? What are the side effects of treatment for testicular cancer?
Icon News

Is follow-up treatment necessary for testicular cancer? What does it involve? Are clinical trials (research studies) available for men with testicular cancer?
Icon News Testicular Cancer Glossary



Back to top

View our Testicular Cancer Online Forum
Testicular Cancer Research & Advancements in treatment
Make A Donation to TC-Cancer.com
TC-Cancer.com and the Testicular Cancer Information and Support Forums, the world's largest testicular cancer forums, were started over a decade ago by a testicular cancer survivor and his friend. TC-Cancer.com and the forums are now supported as a program of the Testicular Cancer Society in concert with the critical support of the voluntary moderators. The Testicular Cancer Society is dedicated to making sure the site and forums are a permanent resource for future patients, survivors and caregivers.

If you would like to make a contribution, then please use the button below and your donation to the Testicular Cancer Society will be marked as being for support of TC-Cancer.com and the forums.
The Testicular Cancer Society is 501(c)(3) public charity, non-profit organization. Your contributions are tax deductible under section 170 of the IRS Code.
Other Resources
Testicular Cancer Society
Personal Stories
Scott's Story
At bedtime one night in March 2003, I suddenly noticed that my right testicle was more than double normal size...
more ยป